My experience shows there is no real difference. Though I haven't done a comparison. However if you do studio you need to do game as well, at least my system wants that. If I don't have game installed BOINC does not see the card.
Studio in theory would be more suited for BOINC.
From NVIDIA forum:
studio drivers are offcycle snapshots of the game ready branch that have a little bit more testing and are only tested on pascal and turing products.
Studio driver is not inferior in its intended purpose - Creative App stability. It will not, however, immediately solve issues experienced while playing games (hotfixes) nor be optimized for both Creative Apps andGames released past the date of issue.
If there are no optimizations or corrective actions to its use with Creative Apps, merely containing game fixes or 3D Profile additions or changes, then it's issued as a Game Ready Driver.
That is the very specific reason to using the Game Ready drivers if you play games either regularly or solely. If, however, you only play a little Minesweeper during your breaks while creating the next fan-based LEGO Avengers clip, then you'll be good until the next version labelled Studio is released.
Because Creative Apps couldn't care less about Gaming's 3D Profiles unless you're running both at the same time, and then they only care about affected system resources...