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Message 28810 - Posted: 26 Feb 2013 | 20:35:45 UTC

we will be posting photos and videos on the facebook page of gpugrid.

If you want to be notified just follow us:
http://www.facebook.com/gpugrid

gdf

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Message 28813 - Posted: 26 Feb 2013 | 20:48:08 UTC - in response to Message 28810.

Just make sure unfacebooked people can see it as well (currently seems to be the case).

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Message 28815 - Posted: 26 Feb 2013 | 20:57:22 UTC

But before that, please submit some WUs. We've dried out...
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Message 28820 - Posted: 26 Feb 2013 | 22:21:18 UTC - in response to Message 28815.

New Wus are coming.

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Message 28821 - Posted: 26 Feb 2013 | 23:12:25 UTC

I am pretty sure you declare me crazy, but I do not have a Facebook account and I do not pretend to open one, because of data privacy protection concerns! However I would like to see the videos and photos as well!

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Message 28823 - Posted: 27 Feb 2013 | 0:19:00 UTC - in response to Message 28821.

No facebook here either and there never will be, don't even wanna go to their goof site and sign in as a guest to see your stuff, if that's how it's gonna work, ain't gonna follow ya, ain't gonna like ya, ain't gonna be a twit and tweet it. Post a link, I'll click it, maybe click some choices on a menu of vids/photos but if you make it more complicated than that then I can't be bothered.

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Message 28824 - Posted: 27 Feb 2013 | 0:42:45 UTC - in response to Message 28823.

Good concept - reach out to new interest, but I couldn't possibly have a Twitter or Facebook account.
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Message 28826 - Posted: 27 Feb 2013 | 1:22:20 UTC

None here either, don't follow the trend setting kids. Are tower computers are going to become a niche market because of them, my youngest son keeps trying to get me to join (he's at Oregon State U right now) but I aint gonna do it.

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Message 28833 - Posted: 27 Feb 2013 | 8:00:58 UTC - in response to Message 28826.

so for videos we keep using youtube. But for photos we use facebook.
Take it as a blog page. I don't use it either for anything else than gpugrid actually.


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Message 28848 - Posted: 27 Feb 2013 | 23:51:37 UTC

Why not place the photo's and video's on the own GPUGRID home page (via a link).
I'm not using any social media and never ever will.
And as I read below I'm not the only one :)
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Message 28875 - Posted: 28 Feb 2013 | 18:16:14 UTC - in response to Message 28848.

To be fair, the Facebook site can be viewed by "outsiders". And it adds this "social stuff" which you won't get with a regular homepage - comments, links, discussions etc.

How much this is worth.. we'll see!

MrS

Ps: Sure, you could add these "social" things to a normal webpage as well (and e.g. use the current forum login for this), but that would actually just create another almost-facebook. And require some effort.
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Message 28884 - Posted: 28 Feb 2013 | 21:51:36 UTC - in response to Message 28875.

You're right. I tried it and you can see the videos and photos without registering, logging in, etc. Thank goodness, for that. The vids, hmmmm, interesting. At first it looked like a thousand Michelin men engaged in an orgy but then I realized it's a model of a giant molecule. So that's how it works huh? The big protein (or whatever) molecule is vibrating about then along comes the smaller one and after a little jostling around the smaller one sort of finds its niche, slot or whatever it's called?

In school I remember graphics of the "lock and key" concept. The receptor molecule has a particular shape like a lock and the incoming molecule exactly fits that shape and it just slides right in. The vids give me the impression that there is far more to it than that (there always is) and that the incoming molecule won't fit into the receiving socket and bind unless the receiver vibrates just the right way?

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Message 28893 - Posted: 1 Mar 2013 | 9:07:19 UTC - in response to Message 28884.

I think it's a matter of time scale: if you look quickly it will seem like the smaller molecule "just snapped in". But the more closer we look (and we need to do that in order to better understand it), the more the process will look like millions of seemingly random bonds, rebonds, bond-attempts etc. But given enough attempts the proper molecule will find the right spot within some typical time frame, whereas most others won't.

How the structure and composition of these molecules affects this bonding / slide in process is one of (or the?) major research topics of GPU-Grid.

(disclaimer: not officially speaking for the project and not totally sure what I said is correct)

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Message 28898 - Posted: 1 Mar 2013 | 11:41:07 UTC

I watched a show on The Science Channel called "The Cell", it was about a skin cell being attacked by a virus and how the virus did it's work and how the cell tried to defend it's self. It blew me away how much they know, one of the most amazing things I saw was the motor protein, their little pairs of legs that attach themselves to packets and 'walk" at 60 cycles a second. 2 pair, 1 for moving forward and the other for backing up to move around objects they bump in to.

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Message 28990 - Posted: 5 Mar 2013 | 10:10:35 UTC
Last modified: 6 Mar 2013 | 10:33:51 UTC

Dagorath, since you seem to be interested in the video I can provide some more info.
The process you are referring to is usually called protein-ligand binding, and the pocket/niche the ligand slips into is called a binding pocket or binding site.
The key and lock model is the oldest but there are now two more models called induced fit and conformational selection.
As far as I understand, induced fit means that the ligand can first bind on the protein and then the protein changes conformation (moves) to improve the binding. The conformational selection means that the protein changes conformations until it matches the ligand and then they bind (like in the key and lock model).
In some/many(?) cases both of the later ones are happening (protein moves around until ligand fits and then the ligand causes conformational change in the protein to fit better).
I am not much of a biologist though so I am not very up to date with any newer models.

Also, yes, motor proteins are awesome :)

(NinjaEdit, thanks to Nate's clarifications)

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